NVVH
Interferon-α (IFN) 1,5 – 3 ME 3x per week gedurende 1 jaar, daarna evt. onderhoud 1x per week of PEGintron; 0,5-1 μg/kg/week18

UTD
IFNa is commonly administered at a dose of two million units/m2 subcutaneously three times a week for 12 to 18 months.